Table 1.
Baseline characteristics of included live kidney donors at the time of donation and matched nondonors at the time of enrolment in population based studies; reported p-values are not adjusted for matching
| Characteristics | Donors (n = 761) | Matched nondonors (n = 1522) | p value |
|---|---|---|---|
| Median (25–75p)/N (%) | Median (25–75p)/N (%) | ||
| Age (years) | 51.9 (42.8–60.1) | 51.0 (37.8–57.9) | p < 0.001 |
| Gender (male) | 318 (41.8) | 636 (41.8) | p = 1.000 |
| Ethnicity (white) | 681 (89.5) | 1434 (94.2) | p = 0.001 |
| BMI (kg/m2) | 25.9 (23.4–28.4) | 25.5 (22.9–28.2) | p = 0.176 |
| Systolic blood pressure (mmHg) | 130.0 (120.0–140.0) | 125.5 (114.0–142.0) | p = 0.010 |
| Diastolic blood pressure (mmHg) | 79.0 (70.0–85.0) | 77.0 (70.0–85.0) | p = 0.964 |
| eGFR (ml/min/1.73 m2) | 92.6 (79.8–103.8) | 90.0 (78.9–102.3) | p = 0.160 |
| Serum glucose (mmol/l) | 4.9 (4.3–5.4) | 5.0 (4.7–5.4) | p = 0.778 |
| Pre-existing hypertensiona | 299 (39.3) | 592 (38.9) | p = 0.891 |
| Pre-existing cardiovascular disease | 13 (1.7) | 28 (1.8) | p = 0.956 |
| Smoking | 400 (52.6) | 867 (57.0) | p = 0.051 |
| Alcohol use | p = 0.560 | ||
| Never/rare | 340 (44.7) | 703 (46.2) | |
| ≤7 glasses/week | 294 (38.6) | 553 (36.3) | |
| >7 glasses/week | 127 (16.7) | 266 (17.5) | |
| Education degree | p = 0.011 | ||
| Primary | 86 (11.3) | 159 (10.4) | |
| Secondary | 418 (54.9) | 782 (51.4) | |
| Tertiary | 257 (33.8) | 581 (38.2) |
aDefined as use of antihypertensive medication, systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg