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. 2020 Jul 28;10:132. doi: 10.1186/s13568-020-01067-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The measurement of UC-MSCs secreted cytokines in vitro and in vivo. a, b The anti-inflammatory cytokines IDO and PEG2 secreted by UC-MSCs were measured by ELISA after being treated with 200 ng/ml IFN-γ. c, d The IL-6 and IL-1β were measured by ELISA in a TNBS-induced colitis mouse model. e, f The IDO and PEG2 were measured by ELISA in aTNBS-induced colitis mouse model. **p < 0.01, * p < 0.05, Student’s t-test. For all experiments, n = 3 healthy donors/group, and data shown are mean ± SD.