Comparison 2. 2 mg vs control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 LDL cholesterol RCTs	3	253	Mean Difference (IV, Fixed, 95% CI)	‐31.00 [‐34.09, ‐27.90]
2.2 Total cholesterol RCTs	3	253	Mean Difference (IV, Fixed, 95% CI)	‐22.77 [‐25.32, ‐20.22]
2.3 HDL cholesterol RCTs	2	200	Mean Difference (IV, Fixed, 95% CI)	6.25 [3.32, 9.19]
2.4 Triglycerides RCTs	2	200	Mean Difference (IV, Fixed, 95% CI)	‐24.63 [‐33.45, ‐15.80]
2.5 LDL‐cholesterol non‐RCTs	33	3594	Mean Difference (IV, Random, 95% CI)	‐37.97 [‐39.53, ‐36.41]
2.6 Total cholesterol non‐RCTs	29	2536	Mean Difference (IV, Fixed, 95% CI)	‐27.36 [‐27.77, ‐26.96]
2.7 HDL‐cholesterol non‐RCTs	28	1996	Mean Difference (IV, Random, 95% CI)	3.98 [2.40, 5.55]
2.8 Triglycerides non‐RCTs	24	1835	Mean Difference (IV, Fixed, 95% CI)	‐16.66 [‐18.00, ‐15.31]
2.9 WDAE	2		Risk Ratio (IV, Fixed, 95% CI)	Totals not selected