Table 3.

Dysfunctional immune system in T2DM patients promotes the pathogenesis of infections.

	Infectious agent	References
Dysfunctional innate immunity
Complement system	Candida spp (albicans, tropicalis, lusitaniae, lipolytica, krusei), Streptococcus pneumoniae, Borrelia burgdorferi, and Escherichia coli	(130–132, 216)
NK cells	Mycobacterium tuberculosis	(203, 213)
Neutrophil	Staphylococcus aureus, Klebsiella pneumoniae, and Burkholderia pseudomallei	(217–221)
Macrophage	Mycobacterium tuberculosis	(222, 223)
ILC3	Mycobacterium tuberculosis	(224)
Dysfunctional adaptive immunity
B cell (humoral immunity)	Staphylococcus aureus, Streptococcus pneumoniae	(199, 201)
CD8+Tcells	Mycobacterium tuberculosis	(203, 213)