Table 2.

Multivariable logistic regression analysis of possible predictors of early neurological deterioration.

	Crude OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Age	1.02 [1.00–1.04]	0.061	1.00 [0.98–1.02]	0.987
Sex	0.65 [0.47–0.91]	0.013	0.69 [0.46–1.03]	0.069
Hypertension	1.57 [1.07–2.30]	0.020	1.37 [0.88–2.13]	0.171
Stroke history	1.55 [1.09–2.21]	0.015	1.51 [1.00–2.28]	0.050
Sustained atrial fibrillation	1.37 [0.95–1.98]	0.088	1.18 [0.72–1.93]	0.522
Initial NIHSS score	1.05 [1.03–1.08]	< 0.001	1.03 [1.00–1.06]	0.043
Use of anticoagulants		< 0.001		< 0.001
No use	Ref	Ref	Ref	Ref
Vitamin K antagonist	0.33 [0.23–0.47]	< 0.001	0.35 [0.23–0.54]	< 0.001
New oral anticoagulant	0.36 [0.18–0.72]	0.004	0.41 [0.19–0.89]	0.024
Systolic blood pressure	1.01 [1.00–1.01]	0.032	1.00 [1.00–1.01]	0.409
Fasting blood sugar*	1.41 [0.77–2.60]	0.266	0.89 [0.48–1.65]	0.705
Troponin I*	1.22 [1.07–1.38]	0.002	1.16 [1.00–1.34]	0.047

NIHSS National Institutes of Health Stroke Scale.

*This variable was transformed into a log scale.