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. 2020 Jul 28;10:12649. doi: 10.1038/s41598-020-69291-6

Table 2.

Variants with association p-value less than 1 × 10–6 in GWAS.

rsID Chr pos A1 A2 FRQ INFO Beta/OR SE p Func.refGene Gene.refGene GeneDetail.refGene
Percentage change of MADRS from baseline
rs11465988 12 66641813 C T 0.9898 0.51 − 51.6 9.2 3.57E−08 Exonic IRAK3
rs17767394 12 66636086 C A 0.9843 0.78 − 32.7 6 8.68E−08 Intronic IRAK3
rs4739050 8 64034747 G A 0.3376 1.02 7.5 1.4 6.06E−08 Intergenic TTPA;YTHDF3-AS1 dist = 36135; dist = 45537
rs151184257 4 105714757 A G 0.9888 0.61 − 40.5 7.9 4.51E−07 Intergenic CXXC4-AS1;TET2 dist = 96008; dist = 352275
rs115141868 2 70816605 A C 0.9898 0.48 − 46.8 9.3 7.65E−07 Intergenic TGFA;ADD2 dist = 35458; dist = 72611
Response status
rs10957273 8 6.4E+07 T C 0.3028 1 0.3 0.2 8.07E−07 Intergenic TTPA;YTHDF3-AS1 dist = 30479; dist = 51193

Note that beta coefficient is reported for percentage change of MADRS score from baseline and OR is reported for responder status.