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. 2020 Jul 28;10:12623. doi: 10.1038/s41598-020-69369-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Prediction of Parkinson’s disease classification. Comparison of Receiver Operating Characteristics (ROC) curves in (a)/(b)/(c) for the produced dAFSi/dRSi/dBSi vs. the state of the art (SoA) algorithms, UPDRS Part III single item 22/23/31 and sum of UPDRS Part III in the $T S_{1}$ cohort for early PD patients vs. HC classification, and the respective comparison curves in d/e/f regarding the de novo PD patients vs. HC classification. AUC values for models are shown with 95% CIs.