Table 1.
Overview of observed interactions between aaRSs and their amino acid ligands.
| Interaction type | ||||||
|---|---|---|---|---|---|---|
| Hydrogen bond | Hydrophobic | Salt bridge | -stacking | Metal complex | Total | |
| Class I | 468 (37.96%) | 550 (44.60%) | 153 (12.41%) | 59 (4.79%) | 3 (0.24%) | 1233 |
| Class II | 856 (59.23%) | 193 (13.36%) | 202 (13.98%) | 144 (9.97%) | 50 (3.46%) | 1445 |
The most prevalent interactions are hydrophobic interactions for Class I aaRSs and hydrogen bonds for Class II aaRSs (typeset in bold). Relative frequencies in respect of all interactions of the aaRS class are given in parentheses.