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Cochlear targets of antioxidants and vasodilators. Antioxidants (1) reduce the apoptotic cochlear damage that follows noise over-exposure, targeting hair cells in the OC, neurons of the spiral ganglion (SG) and stria vascularis (SV), exerting a protective effect over the cochlea and therefore, overhearing. Vasodilators (2), act mainly on the SV, minimizing noise-induced vasoconstriction, restoring the EP, and preserving auditory function.
