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. 2020 Jul 22;11:1034. doi: 10.3389/fphar.2020.01034

Figure 2.

Figure 2

CoQ10 reversed down-regulation of phosphorylated AMPK and phosphorylated YAP, promoted OPA1 protein expression and alleviated vascular-associated inflammatory proteins induced by HFD-treated APOE−/− mice. (A) phosphorylated AMPK and AMPK protein expression ratio. (B) phosphorylated YAP and YAP protein expression ratio. (C) OPA1 protein expression level. (D) IL-6 protein expression level. (E) TNF-α protein expression level. (F) ICAM-1 protein expression level. (G) VCAM-1protein expression level. (H) NLRP3 protein expression level. Results are mean ± SD (n = 10). ##p <0.01 vs. Control group, **p <0.01 vs. HFD group, *p <0.05 vs. HFD group.