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. 2020 Jul 22;11:1034. doi: 10.3389/fphar.2020.01034

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Copyright © 2020 Xie, Wang, Jin, Meng, Liu, Wu and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CoQ10 reversed down-regulation of phosphorylated AMPK and phosphorylated YAP, promoted OPA1 protein expression and decreased ROS generation in ox-LDL-treated HAECs. (A) phosphorylated AMPK and AMPK protein expression ratio. (B) phosphorylated YAP and YAP protein expression ratio. (C) OPA1 protein expression level. (D) The level of ROS. Data in figure represent the mean ± SD from three independent experiments. ^##p < 0.01 vs. Control group, ^**p < 0.01 vs. ox-LDL group, ^*p < 0.05 vs. ox-LDL group.