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. 2020 Jul 22;11:886. doi: 10.3389/fphys.2020.00886

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Copyright © 2020 Tift, Alves de Souza, Weber, Heinrich, Villafuerte, Malhotra, Otterbein and Simonson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) End-tidal carbon monoxide (CO) levels (ppm) in 47 adults from Cerro de Pasco, Peru (high altitude), and 18 adults of mixed ancestry living in San Diego, California, USA (sea level). There was no statistical difference between males (blue) and females (red) from high or low altitude groups (p > 0.8 for both). (B) Relationship between total hemoglobin (g/dl) and the percent carboxyhemoglobin (COHb) in venous blood of adult males (n = 22; blue) and females (n = 21; red) from Cerro de Pasco, Peru (4,330 m).