TABLE 4.

Univariate and multivariate Cox regression analysis for clinical variables.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	P-value	HR (95% CI)	P-value
Age	1.01 (0.99–1.03)	0.45	−	−
Gender	2.92 (0.91–9.38)	0.07	−	−
Tumor grade	1.63 (1.07–2.48)	0.02	1.15 (0.66–1.98)	0.63
Pathological stage	2.51 (1.74–3.61)	< 0.001	3.03 (1.12–8.18)	0.03
T	1.65 (1.13–2.41)	< 0.01	1.05 (0.56–1.62)	0.86
N	1.76 (1.33–2.34)	< 0.001	1.03 (0.60–1.75)	0.93
M	2.93 (1.30–6.58)	< 0.01	1.25 (0.08–2.55)	0.36
Risk score	1.17 (1.12–1.22)	< 0.001	1.13 (1.08–1.19)	< 0.001

The “−” indicates that the value is not available; HR, hazard ratio; CI, confidence interval.