Table 1.
Comparison of indicators between the NCVN and NCVA groups.
| NCVN | NCVA | P | |
|---|---|---|---|
| n | 154 | 184 | |
| Sex (M/F) | 106/48 | 117/67 | 0.311 |
| Age (years) | 52.69 ± 11.45 | 58.90 ± 12.20 | 0.000** |
| Diabetes course (years) | 6.00 (2.00, 11.00) | 9.50 (3.00, 15.75) | 0.005** |
| BMI (kg/m2) | 25.83 ± 3.73 | 26.57 ± 3.78 | 0.075 |
| SBP (mmHg) | 132.47 ± 20.75 | 135.59 ± 20.49 | 0.167 |
| DBP (mmHg) | 83.23 ± 12.64 | 80.93 ± 14.13 | 0.119 |
| Alb (g/L) | 42.07 ± 2.97 | 40.13 ± 3.71 | 0.000** |
| ALT (U/L) | 19.80 (14.80, 28.20) | 17.15 (11.92, 25.30) | 0.011* |
| AST (U/L) | 19.50 (16.40, 23.00) | 19.10 (15.15, 25.35) | 0.759 |
| Cr (μmol/L) | 71.10 (63.60, 80.30) | 73.3 (64.74, 83.58) | 0.081 |
| BUN (mmol/L) | 5.10 (4.47, 6.00) | 5.61 (4.50, 6.80) | 0.030* |
| UA (μmol/L) | 308.18 ± 83.79 | 314.47 ± 92.40 | 0.525 |
| GFR (ml/min) | 97.52 (90.52, 106.89) | 90.91 (76.53, 102.48) | 0.000** |
| TC (mmol/L) | 4.80 ± 1.14 | 4.79 ± 1.56 | 0.929 |
| TG (mmol/L) | 1.49 (0.99, 2.35) | 1.43 (1.07, 2.12) | 0.993 |
| HDL-C (mmol/L) | 1.11 (0.91, 1.47) | 1.13 (0.91, 1.68) | 0.838 |
| LDL-C (mmol/L) | 2.68 ± 1.06 | 2.65 ± 1.24 | 0.822 |
| FBG (mmol/L) | 7.75 (6.36, 9.90) | 8.79 (6.67, 11.62) | 0.005** |
| HOMA-IR | 2.78 (1.58, 5.01) | 3.36 (1.87, 6.67) | 0.130 |
| HbA1c (%) | 8.25 ± 1.94 | 9.30 ± 1.95 | 0.000** |
| PPGE (mmol/L) | 3.38 ± 1.79 | 3.49 ± 1.63 | 0.559 |
| SDBG (mmol/L) | 2.13 ± 1.07 | 2.55 ± 1.04 | 0.001** |
| LAGE (mmol/L) | 6.25 ± 3.04 | 7.25 ± 3.02 | 0.004** |
| MBG (mmol/L) | 9.68 ± 2.21 | 10.43 ± 2.44 | 0.006* |
| TT3 (nmol/L) | 1.49 (1.32, 1.66) | 1.41 (1.30, 1.63) | 0.155 |
| TT4 (nmol/L) | 89.50 (78.92, 101.85) | 90.31 (78.97, 100.85) | 0.818 |
| TSH (μIU/mL) | 1.99 (1.12, 2.86) | 2.02 (1.40, 2.83) | 0.373 |
| 25(OH)D3 (ng/mL) | 16.79 (13.88, 21.39) | 15.43 (12.35, 19.65) | 0.026* |
| SOD (μmol/L) | 59.48 ± 8.91 | 60.25 ± 9.31 | 0.442 |
| GSH (μmol/L) | 19.46 (10.95, 44.47) | 18.85 (12.13, 36.67) | 0.744 |
| MDA (μmol/L) | 13.47 (8.09, 21.95) | 17.81 (9.84, 23.57) | 0.030* |
| TNF-α (μmol/L) | 28.24 (18.29, 42.50) | 34.16 (19.93, 48.12) | 0.117 |
| LogTXNIP (pg/mL) | 1.53 ± 0.40 | 1.64 ± 0.41 | 0.018* |
| Use of insulin (Y/N) | 81/73 | 128/56 | 0.001** |
| Use of metformin (Y/N) | 103/51 | 91/93 | 0.001** |
P < 0.05,
P < 0.01 NCVA vs. NCVN.
BMI, Body mass index; SBP, Systolic blood pressure; DBP, Diastolic blood pressure; Alb, Serum albumin; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; TG, Triglycerides; TC, Total cholesterol; HDL-C, High density lipoprotein cholesterol; LDL-C, Low density lipoprotein cholesterol; Cr, Creatinine; BUN, Blood urea nitrogen; GFR, Glomerular filtration rate; UA, Uric acid; FBG, Fasting blood glucose; HbAlc, Glycated hemoglobin; HOMA-IR, Insulin resistance index; TT3, Total triiodothyronine; TT4, Total thyroxine; TSH, Thyroid stimulating hormone; PPGE, Mean post-prandial glucose excursion; SDBG, Standard deviation of blood glucose; LAGE, Largest amplitude of glucose excursion; MBG, Mean blood glucose; SOD, Superoxide dismutase; MDA, Malondialdehyde; GSH, Glutathione; TNF-α, Tumor necrosis factor alpha.