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. 2020 Jul 22;11:1129. doi: 10.3389/fimmu.2020.01129

Table 2.

Sarcoidosis characteristics at enrollment/time of blood draw in cases and controls.

Cases Controls p-value*
PFT
Decrease
PFT
Increase
N = 22 N = 11 N = 10
Age (mean years, SD) 56 (12) 50 (13) 46 (9) 0.082
Female (%) 16 (73) 4 (36) 3 (30) 0.089
Race (%) 0.37
African American 1 (5) 2 (18) 0 (0)
White 19 (86) 7 (64) 8 (80)
Hispanic 2 (9) 0 (0) 0 (0)
Other 0 (0) 2 (18) 2 (20)
Ever Smokers 11 (50) 6 (55) 4 (40) 0.64
Immunosuppression Use (%) 9 (41) 6 (55) 0 (0) N/A
Extra-thoracic Organ Involvement (%) 75 78 10 0.00056
Initial Visit PFTs: Mean (SD)
FVC %predicted 97 (16) 80 (18) 99 (13) 0.012
FEV1 %predicted 89 (18) 75 (24) 89 (17) 0.11
FEV1/FVC 0.72 (0.085) 0.72 (0.14) 0.71 (0.081) 0.95
DLCO %predicted 74 (16) 59 (13) 79 (12) 0.011
TLC %predicted 99 (11) 83 (17) 93 (13) 0.027
*

p-values are for comparisons between cases and controls.

p-values for PFTs compare the controls and the cases as two separate groups.

N/A, not applicable.