Table 2.
Cases | Controls | p-value* | ||
---|---|---|---|---|
PFT Decrease |
PFT Increase |
|||
N = 22 | N = 11 | N = 10 | ||
Age (mean years, SD) | 56 (12) | 50 (13) | 46 (9) | 0.082 |
Female (%) | 16 (73) | 4 (36) | 3 (30) | 0.089 |
Race (%) | 0.37 | |||
African American | 1 (5) | 2 (18) | 0 (0) | |
White | 19 (86) | 7 (64) | 8 (80) | |
Hispanic | 2 (9) | 0 (0) | 0 (0) | |
Other | 0 (0) | 2 (18) | 2 (20) | |
Ever Smokers | 11 (50) | 6 (55) | 4 (40) | 0.64 |
Immunosuppression Use (%) | 9 (41) | 6 (55) | 0 (0) | N/A |
Extra-thoracic Organ Involvement (%) | 75 | 78 | 10 | 0.00056 |
Initial Visit PFTs: Mean (SD) | ||||
FVC %predicted | 97 (16) | 80 (18) | 99 (13) | 0.012 |
FEV1 %predicted | 89 (18) | 75 (24) | 89 (17) | 0.11 |
FEV1/FVC | 0.72 (0.085) | 0.72 (0.14) | 0.71 (0.081) | 0.95 |
DLCO %predicted | 74 (16) | 59 (13) | 79 (12) | 0.011 |
TLC %predicted | 99 (11) | 83 (17) | 93 (13) | 0.027 |
p-values are for comparisons between cases and controls.
p-values for PFTs compare the controls and the cases as two separate groups.
N/A, not applicable.