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. 2020 Jul 22;11:1129. doi: 10.3389/fimmu.2020.01129

Table 4.

Results from correlation analyses and regression models for T-bet+ frequencies of RORγt+Th17.0 cells and IFN-γ-related blood markers.

Outcome Main Predictor Adj β-coeff 95% CI Adj p-value Adj r value Unadj r value
%T-bet± of Log10[CXCL9]§ 22 (14, 31) 1.5 × 10−5 0.66 0.65
RORγt±Th17.0 cells Log10[CXCL10] 23 (3.6, 42) 0.022 0.47 0.41
Log10[CXCL11] 30 (11, 49) 0.0028 0.51 0.50
IFN Factor†† 6.9 (0.81, 13) 0.028 0.37 0.58
JAK2‡‡ 4.2 (2.5, 10) 0.034 0.29 0.42
TAP1‡‡ 4.8 (0.25, 9.3) 0.041 0.26 0.42

β-coefficient is adjusted for age, race, sex, and immunosuppression use.

Unadjusted Pearson r coefficient.

§

Serum chemokine values were log10-transformed.

††

The “IFN Factor” = a three gene mean of GBP1, STAT1, and STAT2 previously measured from whole blood.

‡‡

Whole blood gene expression values in the form of log2[relative expression].

Adj, Adjusted; CI, Confidence Interval; Coeff, Coefficient; Unadj, Unadjusted.

Bold values indicates p-values for adjusted β-coeffecients.