Table 4.
Results from correlation analyses and regression models for T-bet+ frequencies of RORγt+Th17.0 cells and IFN-γ-related blood markers.
| Outcome | Main Predictor | Adj β-coeff† | 95% CI | Adj p-value | Adj r value | Unadj r value‡ |
|---|---|---|---|---|---|---|
| %T-bet± of | Log10[CXCL9]§ | 22 | (14, 31) | 1.5 × 10−5 | 0.66 | 0.65 |
| RORγt±Th17.0 cells | Log10[CXCL10] | 23 | (3.6, 42) | 0.022 | 0.47 | 0.41 |
| Log10[CXCL11] | 30 | (11, 49) | 0.0028 | 0.51 | 0.50 | |
| IFN Factor†† | 6.9 | (0.81, 13) | 0.028 | 0.37 | 0.58 | |
| JAK2‡‡ | 4.2 | (2.5, 10) | 0.034 | 0.29 | 0.42 | |
| TAP1‡‡ | 4.8 | (0.25, 9.3) | 0.041 | 0.26 | 0.42 |
β-coefficient is adjusted for age, race, sex, and immunosuppression use.
Unadjusted Pearson r coefficient.
Serum chemokine values were log10-transformed.
The “IFN Factor” = a three gene mean of GBP1, STAT1, and STAT2 previously measured from whole blood.
Whole blood gene expression values in the form of log2[relative expression].
Adj, Adjusted; CI, Confidence Interval; Coeff, Coefficient; Unadj, Unadjusted.
Bold values indicates p-values for adjusted β-coeffecients.