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. 2020 Jul 22;12:193. doi: 10.3389/fnagi.2020.00193

Table 1.

Demographic and clinical characteristics of the subjects with different vascular risk factor (VRF) burdens who provided serum samples.

Characteristic Low-risk group (n = 24) Medium-risk group (n = 27) High-risk group (n = 14) F or χ2 P-value
Sex
   Malea [N, (%)] 9 (13.85) 19 (29.23) 13 (20.00) 12.69 <0.01
   Femalea [N, (%)] 15 (23.08) 8 (12.31) 1 (1.54) 12.69 <0.01
Agea (x¯ ± s, years) 58.54 ± 5.48 65.59 ± 6.51 72.57 ± 5.76 25.00 <0.01
Education (x¯ ± s, years) 9.13 ± 2.88 7.93 ± 2.29 10.21 ± 3.02 3.55 <0.05
Hypertensiona [N, (%)] 4 (6.15) 16 (24.62) 10 (15.38) 13.86 <0.01
DMa [N, (%)] 0 (0.00) 3 (4.62) 4 (6.15) 7.52 <0.05
CVDa [N, (%)] 1 (1.54) 2 (3.08) 6 (9.23) 12.70 <0.01
AFa [N, (%)] 0 (0.00) 0 (0.00) 4 (6.15) 15.53 <0.01
Current Smokinga [N, (%)] 0 (0.00) 8 (12.31) 4 (6.15) 8.62 <0.05
LVHa [N, (%)] 1 (1.54) 0 (0.00) 0 (0.00) 1.74 0.42
SBPa (mmHg) 126.38 ± 9.22 138.41 ± 13.96 134.64 ± 13.33 6.24 <0.01
BUN (x¯ ± s, mmol/L) 5.19 ± 1.35 5.71 ± 1.92 5.95 ± 1.44 1.23 0.33
UA (x¯ ± s, μmol/L) 310.58 ± 72.61 344.00 ± 107.71 377.57 ± 72.01 2.59 0.08
TC (x¯ ± s, mmol/L) 4.37 ± 0.86 4.38 ± 1.06 3.90 ± 0.88 1.39 0.26
TG (x¯ ± s, mmol/L) 1.35 ± 0.73 1.51 ± 0.74 2.24 ± 3.57 1.19 0.31
HDL (x¯ ± s, mmol/L) 1.41 ± 0.36 1.33 ± 0.44 1.01 ± 0.37 4.57 <0.05
LDL (x¯ ± s, mmol/L) 2.44 ± 0.66 2.46 ± 0.78 2.13 ± 0.53 1.21 0.31
APO-A (x¯ ± s, mmol/L) 1.56 ± 0.36 1.52 ± 0.34 1.19 ± 0.32 5.59 <0.01
FSRP (x¯ ± s, %) 3.04 ± 1.30 8.70 ± 2.20 20.57 ± 4.40 200.22 <0.01

Abbreviations: DM, diabetes mellitus; CVD, cardiovascular disease; AF, atrial fibrillation; LVH, left ventricular hypertrophy on ECG; SBP, systolic blood pressure; BUN, blood urea nitrogen; UA, uric acid; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; APO-A, apolipoprotein-A; FSRP, Framingham stroke risk profile. Note: “a” indicates the risk factors for Framingham stroke risk profile. The data are presented as means ± SD or number of cases (%).