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. 2006 Oct 18;2006(4):CD004788. doi: 10.1002/14651858.CD004788.pub2

Assalia 1993.

Methods Single‐centre randomised trial.
Generation of allocation: unclear. 
 Allocation concealment: unclear. 
 Blinding: not performed. 
 Follow‐up: unclear. Drop‐outs: none mentioned.
Intention‐to‐treat: not mentioned. 
 Sample size calculations: no.
Participants Elective cholecystectomy for symptomatic cholelithiasis.
In‐ and exclusion criteria: not mentioned.
Comparability groups: well matched.
Interventions SIC versus OC.
Minicholecystectomy: initial 5 cm (no preoperative ultrasound location), extended in stages each 1 cm long. Retrograde (fundus down) technique was performed.
Open cholecystectomy: technique was left to the individual surgeon. Length of incision: offer comfortable exposure, however, not too generous.
Antibiotic prophylaxis: yes.
Intra‐operative cholangiography: selectively carried out according to clinical and laboratory indications.
Outcomes Primary and secondary outcome: not mentioned.
Outcomes: difficulty of the procedure, operative time, degree of pain, total amount of analgesia, hospital stay, patient satisfaction, physical activity limitations.
Duration of follow‐up: 2 weeks.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear
Blinding? 
 All outcomes High risk  
Free of selective reporting? High risk  
Free of other bias? High risk short follow‐up of 2 weeks