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. 2006 Oct 18;2006(4):CD004788. doi: 10.1002/14651858.CD004788.pub2

O'Dwyer 1992.

Methods Two‐centre trial.
Generation of allocation: unclear. 
 Allocation concealment: adequate (sealed envelope). 
 Blinding: not performed. 
 Follow‐up: unclear. Drop‐outs: none mentioned.
Intention‐to‐treat: not mentioned. 
 Sample size calculations: no.
Participants Patients having cholecystectomy for symptomatic gallstones.
In‐ and exclusion criteria: well described.
Comparability groups: well matched.
Interventions SIC versus OC.
SIC: through 6 cm incision, rectus muscle divided.
OC: not further described.
Antibiotic prophylaxis: not mentioned.
Routine operative cholangiography in all patients.
Outcomes Primary and secondary outcome: not specified.
Outcome measures: pulmonary, function tests, analgesia requirements, hospital stay.
Duration of follow‐up: hospital stay.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate
Blinding? 
 All outcomes High risk  
Free of selective reporting? High risk  
Free of other bias? High risk short follow‐up (hospital stay)