Table 1:
Characteristicsa | Valuebc |
---|---|
Age in years, mean (range) | 56 (20–84) |
Sex | |
Male | 29 (63) |
Female | 17 (37) |
Race | |
White | 32 (70) |
Black | 4 (9) |
Asian, American Indian, or Alaska Native | 3 (7) |
Not Reported | 7 (15) |
Ethnicity | |
Hispanic or Latino | 4 (9) |
Non-Hispanic/ Latino | 41 (89) |
Not Reported | 2 (4) |
Geographic Region | |
West Coast | 15 (33) |
Mountain West | 12 (26) |
Midwest | 6 (13) |
South | 5 (11) |
Northeast | 8 (17) |
HS degree or higherd | 45 (98) |
Enrolled in Medicared | 17 (37) |
Primary cause of lung injury | |
Pneumonia | 32 (70) |
Aspiration | 7 (15) |
Nonpulmonary Sepsis | 3 (7) |
Other Causes | 4 (9) |
Assessments and measurements | |
APACHE III score, mean (SD) | 98 (26) |
Total SOFA score, mean (SD) | 8 (3) |
Tidal volume - ml/kg of predicted body weight, mean (SD) | 6.1 (.7) |
FIO2, mean (SD) | 0.77 (.21) |
Inspiratory plateau pressure -- cm of water, mean (SD) | 25.7 (5.5) |
PEEP-- cm of water, mean (SD) | 12.6 (3.4) |
Pao2:FIO2, mean (SD)e | 98 (31) |
Randomization Assignment | |
Neuromuscular Blockade | 20 (43) |
Usual Care | 26 (57) |
Days post-enrollment at time of interview, median (IQR) | 360 (324–385) |
Disability Score at 6-month follow-up, mean (SD)f | 3.24 (±2.4) |
Characteristics were measured at time of ROSE randomization unless otherwise noted.
Data are presented as number (percentage) unless otherwise noted; percentages may sum to greater than 100% due to rounding.
Differences between respondents and non-respondents are described in Appendix B.
Medicare enrollment information and educational attainment were assessed at 3-month follow-up.
If an arterial blood gas was not available at randomization, the ratio was inferred from oxygen saturation as measured by pulse oximetry.
The disability score ranges from 0 to 10 and is the number of those 10 ADL/IADL items on which the respondent or their proxy reported difficulty due to health conditions at 6 months post-randomization, with higher scores representing worse disability, and scores of 4 or greater interpretable as representing severe disability.