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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Life Sci Space Res (Amst). 2020 May 22;26:62–68. doi: 10.1016/j.lssr.2020.04.002

Table 3.

Histopathological scoring of interstitial fibrosis at 12 months after exposure to 16O (600 MeV/n, 0.5 Gy) or protons (250 MeV, 0.5 Gy)

Dose group Scores of individual rats
0 Gy 0, 0, 0, 0, 0, 0, 0, 1, 1, 1
16O (0.5 Gy) 0, 0, 0, 0, 0, 0, 0, 0.5, 1, 1
Protons (0.5 Gy) 0, 0, 0, 0, 0, 0, 0, 0, 0.5, 0.5, 0.5, 1

Longitudinal sections of heart were scored for interstitial fibrosis using the following grading system: 0 = no lesions; 0.5–1 = mild changes; 1.5–2 = moderate changes; 2.5–3 = marked changes; 3.5–4 = severe changes.