1. Study populations.

study ID	intervention	[n] screened	[n] randomised	[n] safety	[n] ITT	[n] finishing study	comments
Selva 2002	Intervention (I): L‐thyroxine 50 mcg/day Control1 (C1): L‐thyroxine 37.5mcg/day Control 2 (C2): loading dose 50 mcg/day for 3 days, followed by 37.5mcg/day	I: nr C1: nr C2: nr	I: 15 C1: 15 C2: 17 Total: 47	I: nr C1: nr C2: nr	I: nr C1: nr C1: nr	I: 15 C1: 15 C2: 17 Total: 47

nr = not reported