| 3.1 Blood phenylalanine level (micromol/L) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.1.1 Blood phenylalanine level (0 to 3 months) |
1 |
132 |
Mean Difference (IV, Fixed, 95% CI) |
‐127.10 [‐185.04, ‐69.16] |
| 3.1.2 Blood phenylalanine levels (7 to 12 months) |
1 |
132 |
Mean Difference (IV, Fixed, 95% CI) |
‐157.30 [‐217.18, ‐97.42] |
| 3.1.3 Blood phenylalanine level (at 2 years) |
1 |
132 |
Mean Difference (IV, Fixed, 95% CI) |
‐84.70 [‐158.02, ‐11.38] |
| 3.1.4 Blood phenylalanine level (at 3 years) |
1 |
128 |
Mean Difference (IV, Fixed, 95% CI) |
‐48.40 [‐125.39, 28.59] |
| 3.1.5 Blood phenylalanine level (at 4 years) |
1 |
127 |
Mean Difference (IV, Fixed, 95% CI) |
‐78.70 [‐174.49, 17.09] |
| 3.1.6 Blood phenylalanine level (at 5 years) |
1 |
127 |
Mean Difference (IV, Fixed, 95% CI) |
‐72.60 [‐162.35, 17.15] |
| 3.2 Weight (kg) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.2.1 Weight (0 to 3 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.20 [‐0.47, 0.07] |
| 3.2.2 Weight (4 to 6 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.20 [‐0.56, 0.16] |
| 3.2.3 Weight (7 to 12 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.10 [‐0.58, 0.38] |
| 3.3 Intelligence quotient (IQ) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.3.1 IQ at 4 years |
1 |
111 |
Mean Difference (IV, Fixed, 95% CI) |
3.00 [‐2.77, 8.77] |
| 3.3.2 IQ at 6 years |
1 |
132 |
Mean Difference (IV, Fixed, 95% CI) |
2.00 [‐3.41, 7.41] |
| 3.4 Calorie intake (kcal/kg) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.4.1 Calorie intake (0 to 3 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐1.00 [‐11.06, 9.06] |
| 3.4.2 Calorie intake (4 to 6 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐3.00 [‐10.12, 4.12] |
| 3.4.3 Calorie intake (7 to 12 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.00 [‐12.51, 0.51] |
| 3.5 Protein intake (g/kg) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.5.1 Protein intake (0 to 3 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
0.00 [‐0.40, 0.40] |
| 3.5.2 Protein intake (4 to 6 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.10 [‐0.33, 0.13] |
| 3.5.3 Protein intake (7 to 12 months) |
1 |
88 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.10 [‐0.31, 0.11] |
| 3.6 Phenylalanine intake (mg/day) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 3.6.1 At 15 months of age |
1 |
151 |
Mean Difference (IV, Fixed, 95% CI) |
‐64.00 [‐67.54, ‐60.46] |
| 3.6.2 At 21 months of age |
1 |
138 |
Mean Difference (IV, Fixed, 95% CI) |
‐64.00 [‐68.81, ‐59.19] |
| 3.6.3 At 27 months of age |
1 |
141 |
Mean Difference (IV, Fixed, 95% CI) |
‐88.00 [‐92.56, ‐83.44] |
| 3.6.4 At 33 months of age |
1 |
139 |
Mean Difference (IV, Fixed, 95% CI) |
‐73.00 [‐77.85, ‐68.15] |
| 3.6.5 At 39 months of age |
1 |
134 |
Mean Difference (IV, Fixed, 95% CI) |
‐80.00 [‐84.94, ‐75.06] |
| 3.6.6 At 45 months of age |
1 |
141 |
Mean Difference (IV, Fixed, 95% CI) |
‐58.00 [‐63.95, ‐52.05] |
| 3.6.7 At 51 months of age |
1 |
125 |
Mean Difference (IV, Fixed, 95% CI) |
‐83.00 [‐88.97, ‐77.03] |
| 3.6.8 At 57 months of age |
1 |
119 |
Mean Difference (IV, Fixed, 95% CI) |
‐69.00 [‐75.61, ‐62.39] |
| 3.6.9 At 63 months of age |
1 |
115 |
Mean Difference (IV, Fixed, 95% CI) |
‐106.00 [‐112.54, ‐99.46] |
| 3.6.10 At 69 months of age |
1 |
117 |
Mean Difference (IV, Fixed, 95% CI) |
‐77.00 [‐90.18, ‐63.82] |
