2. Summary of included studies.
Characteristic | n | Percentage |
Underlying condition | ||
Cancer HIV/AIDS ICU Mixed at‐risk Organ transplant |
23 1 16 7 2 |
46.9% 2.0% 32.7% 14.3% 4.1% |
Age of patients | ||
Adult Neonate Pediatric Mixed Unknown |
26 3 3 5 12 |
53.1% 6.1% 6.1% 10.2% 24.5% |
Study design | ||
Prospective consecutive Retrospective consecutive Retrospective case‐control |
26 12 11 |
53.1% 24.5% 22.4% |
Fungal type | ||
Aspergillus only Candida only PJP only Mixed fungal types |
12 10 3 24 |
24.5% 20.4% 6.1% 49.0% |
Test brand | ||
Fungitell Glucatell Fungitec‐G Wako Dynamiker Fungus |
36 5 3 3 2 |
73.5% 10.2% 6.1% 6.1% 4.1% |
Sampling strategy | ||
Single sample Multiple samples Unknown |
20 26 3 |
40.8% 53.1% 6.1% |
Reference standard used | ||
EORTC Proven Candida PJP microscopy/PCR Study‐specific |
36 8 3 2 |
73.5% 16.3% 6.1% 4.1% |
Low risk of bias | ||
Participant selection Index test Reference standard Flow and timing |
35 49 41 41 |
71.4% 100.0% 83.7% 83.7% |
EORTC: European Organization for Research and Treatment of Cancer; ICU: intensive care unit; PCR: polymerase chain reaction; PJP: Pneumocystis jirovecii pneumonia.