| Study | Reason for exclusion |
|---|---|
| Acosta 2012 | Unable to determine cell counts |
| Akamatsu 2007 | Assay cut‐off did not follow manufacturer's recommendations |
| Azoulay 2016 | Possible IFI included in case definition; unable to separate |
| Badiee 2016 | Assay cut‐off did not follow manufacturer's recommendations |
| Bellanger 2011 | Study utilizes 2 cut‐off values for determining positivity of BDG |
| Bhaskaran 2017 | Only bronchoalveolar lavage fluid results given |
| Boluk 2016 | Included BDG test as part of reference standard |
| Brasier 2015 | Unable to determine cell counts |
| Calitri 2017 | Unable to determine cell counts |
| Dobias 2018 | Study population did not match inclusion guidelines |
| Donato 2017 | Study population did not match inclusion guidelines |
| Ellis 2008 | Possible IFI included in case definition; unable to separate |
| Goudijl 2013 | Assay cut‐off did not follow manufacturer's recommendations |
| Guitard 2016 | Unable to determine cell counts |
| Han 2015 | Unable to determine cell counts |
| Hartl 2018 | Possible IFI included in case definition; unable to separate |
| Heyland 2011 | Did not follow EORTC guidelines; questionable patient population |
| Hoenigl 2014 | Only bronchoalveolar lavage fluid results given |
| Ji 2008 | Unable to determine cell counts |
| Kato 2010 | Included BDG as part of reference standard |
| Kishimoto 2019 | Study population did not match inclusion guidelines |
| Kumar 2018 | Study population did not match inclusion guidelines |
| Lahmer 2016c | Unable to determine cell counts |
| Lahmer 2017 | Study population did not match inclusion guidelines |
| Leon 2009 | Assay cut‐off did not follow manufacturer's recommendations |
| Leon 2012 | Unable to determine cell counts |
| Levesque 2015 | Unable to determine cell counts |
| Levesque 2017 | Unable to determine cell counts |
| Matsumara 2011 | Study utilizes 2 cut‐off values for determining positivity of BDG |
| McKeating 2018 | Unable to determine patient population |
| Metan 2016 | Unable to determine cell counts |
| Montagna 2012 | Unable to determine cell counts |
| Mutschlechner 2015 | Unable to determine cell counts |
| Oz 2014 | Possible IFI included in case definition; unable to separate |
| Pazos 2005 | Assay cut‐off did not follow manufacturer's recommendations |
| Pazos 2006 | Assay cut‐off did not follow manufacturer's recommendations |
| Picardi 2019 | Not a diagnostic accuracy study |
| Presterl 2009 | Assay cut‐off did not follow manufacturer's recommendations |
| Ramos 2017 | Cannot separate confirmed Candida cases from probable Candida cases |
| Rhein 2014 | Only cerebrospinal fluid results given |
| Sax 2011 | Did not follow EORTC guidelines |
| Shi 2015 | Did not follow EORTC guidelines |
| Su 2017 | Did not follow EORTC guidelines |
| Sulahian 2014 | Unable to determine cell counts |
| Tasaka 2007 | Unable to determine cell counts |
| Watanabe 2009 | Assay cut‐off did not follow manufacturer's recommendations |
| White 2018 | Unable to determine cell counts |
| Wood 2013 | Cannot separate confirmed PJP cases from probable cases |
| Yang 2012 | Did not follow EORTC guidelines |
| Yu 2010 | Unable to determine cell counts |
| Zheng 2017 | Assay cut‐off did not follow manufacturer's recommendations |
BDG: beta‐D‐glucan test; EORTC: European Organization for Research and Treatment of Cancer; IFI: invasive fungal infection; PJP: Pneumocystis jirovecii pneumonia.