Trial ID	Intervention(s) and comparator(s)	Duration of intervention/duration of follow‐upa	Description of participants	Trial period	Country	Setting	Ethnic groups (%)	Duration of diabetes (mean years (SD))
Ensor 2015	I: sucralose	10 months/10 months	Men and women with type 2 diabetes	‐	India, USA	Outpatients	Asian: 72 Caucasian (understood to be white): 12 Latino: 11 Black: 5	‐
	C: D‐tagatose							‐
Barriocanal 2008	I: steviol glycoside	3 months/3 months	Men and women with type 1 diabetes, type 2 diabetes, and healthy participants	2005 to 2006b	Paraguay	Outpatients	‐	Type 1 diabetes patients: > 5 years; type 2 diabetes patients: > 1 year and < 10 years
	C: placebo						‐	Type 1 diabetes patients: > 5 years; type 2 diabetes patients: > 1 year and < 10 years
Maki 2008	I: rebaudioside A	16 weeks/16 weeks	Men and women with type 2 diabetes	2006 to 2007b	USA	Outpatients	Non‐Hispanic white: 68 African‐American: 22 Hispanic: 8 Other: 2	> 1 year
	C: placebo						Non‐Hispanic white: 73 African‐American: 19 Hispanic: 6 Other: 2	> 1 year
Grotz 2003	I: sucralose	13 weeks/17 weeks	Men and women with type 2 diabetes	‐	USA	Outpatients	White: 76 Black: 13 Asian: 5 Hispanic: 6 Other: 0	9.3 (6.9)
	C: placebo						White: 83 Black: 6 Asian: 3 Hispanic: 7 Other: 1	10.17 (7.7)
Colagiuri 1989	I: aspartame	6 weeks/6 weeks	Men and women with type 2 diabetes	‐	Australia	Outpatients	‐	8.6 (5.0)
	C: sucrose						‐	8.6 (5.0)
Cooper 1988	I: saccharin and starch	6 weeks/6 weeks	Men and women with type 2 diabetes	‐	Australia	Outpatients	‐	‐
	C: sucrose						‐	‐
Chantelau 1985	I: sodium‐cyclamate	4 weeks/4 weeks	Men and women with type 1 diabetes	1985	Germany	Outpatients	‐	> 1 year
	C: sucrose						‐	> 1 year
Nehrling 1985	I: aspartame	18 weeks/18 weeks	Adult participants with type 1 or type 2 diabetes	‐	USA	Outpatients	‐	‐
	C: placebo (cornstarch)						‐	‐
Stern 1976	I: aspartame	13 weeks/13 weeks	Men and women with type 2 diabetes	‐	USA	Outpatients	‐	‐
	C: placebo						‐	‐
‐: denotes not reported aFollow‐up under randomised conditions until end of trial (= duration of intervention + follow‐up postintervention or identical to duration of intervention). bDates were not clearly stated. C: comparator; I: intervention; SD: standard deviation.