Trial ID | Intervention(s) and comparator(s) | Participants included in analysis (N) | Participants with at least 1 hypoglycaemic episode (N) | Participants with at least 1 hypoglycaemic episode (%) | Participants with at least 1 nocturnal hypoglycaemic episode (N) | Participants with at least 1 nocturnal hypoglycaemic episode (% participants) | Participants with at least 1 severe/serious hypoglycaemic episode (N) | Participants with at least 1 severe/serious hypoglycaemic episode (%) |
Ensor 2015 | I: sucralose | 207 | 0 | 0 | 0 | 0 | 0 | 0 |
C: D‐tagatose | 185 | 0 | 0 | 0 | 0 | 0 | 0 | |
Barriocanal 2008 | I: steviol glycoside | 23 | 0 | 0 | 0 | 0 | 0 | 0 |
C: placebo | 23 | 0 | 0 | 0 | 0 | 0 | 0 | |
Maki 2008 | I: rebaudioside A | 60 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: placebo | 62 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Grotz 2003 | I: sucralose | 67 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: placebo | 69 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Colagiuri 1989 | I: aspartame | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: sucrose | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Cooper 1988 | I: saccharin and starch | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: sucrose | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Chantelau 1985 | I: sodium‐cyclamate | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: sucrose | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Nehrling 1985 | I: aspartame | 30 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: placebo (cornstarch) | 33 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
Stern 1976 | I: aspartame | 36 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
C: placebo | 33 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | |
‐: denotes not reported C: comparator; I: intervention; N: number of participants. |