| Study | Reason for exclusion |
|---|---|
| ACTRN12618000862246 | Duration of intervention < 4 weeks |
| Anonymous 1979 | Not a primary study (narrative overview) |
| Barbosa Martín 2014 | Not a primary study (narrative overview) |
| Bastaki 2015 | Not a primary study (narrative overview) |
| Baturina 2004 | Duration of intervention < 4 weeks |
| Beringer 1973 | Not a primary study (narrative overview) |
| Blackburn 1997 | Participants were non‐diabetic |
| Bloomgarden 2011 | Not a primary study (narrative overview) |
| Chantelau 1986 | Not a primary study (narrative overview) |
| Corfe 1858 | Not a primary study (narrative overview) |
| Deschamps 1971 | Duration of intervention < 4 weeks |
| Dinkovski 2017 | Not a primary study (narrative overview) |
| EUCTR2006‐002395‐18‐DK | Trial was never started (based on information from authors: "the study have never been executed"). |
| Farkas 1965 | Not a randomised controlled trial |
| Ferland 2007 | Duration of intervention < 4 weeks |
| Ferri 2006 | Participants were non‐diabetic. |
| Fukuda 2010 | Duration of intervention < 4 weeks |
| Gapparov 1996 | Not a primary study (narrative overview) |
| Healy 2013 | Not a primary study (narrative overview) |
| Heraud 1976 | Not a primary study (narrative overview) |
| IRCT2015091513612N6 | Intervention unclear ("8 candies with no sugar, 6 biscuits, and 5 sugar bars, daily") |
| Kanders 1988 | Participants were non‐diabetic |
| Knopp 1976 | Participants were non‐diabetic |
| Leon 1989 | Participants were non‐diabetic |
| Macdonald 1970 | Not a primary study (narrative overview) |
| Madjd 2017 | Intervention unclear ("subjects were instructed to continue to drink DBs (250 mL) once daily after lunch (main meal) 5 times a week") |
| Maersk 2012 | Participants were non‐diabetic |
| Maki 2009 | Duration of intervention < 4 weeks |
| Masic 2017 | Participants were non‐diabetic |
| Mazovetskii 1976 | Not a primary study (narrative overview) |
| McCann 1956 | Not a randomised controlled trial |
| Mehnert 1975 | Not a primary study (narrative overview) |
| Mehnert 1979 | Not a primary study (narrative overview) |
| Morris 1993 | Participants were non‐diabetic |
| NCT01324921 | Duration of intervention < 4 weeks |
| NCT02252952 | Participants were non‐diabetic |
| NCT02412774 | Intervention unclear ("diet beverages after the main meal") |
| NCT02487537 | Participants were non‐diabetic |
| NCT02813759 | Not a randomised clinical trial |
| NCT03680482 | Duration of intervention < 4 weeks |
| Noren 2014 | Not a randomised controlled trial |
| Odegaard 2017 | Intervention unclear ("diet beverage (DB) of choice ") |
| PACTR201410000894447 | Duration of intervention < 4 weeks |
| Parimalavalli 2011 | Not a randomised clinical trial |
| Peters 2014 | Participants were non‐diabetic |
| Peters 2016 | Participants were non‐diabetic |
| Piernas 2011 | Participants were non‐diabetic |
| Piernas 2013 | Participants were non‐diabetic |
| Prols 1973 | Duration of intervention < 4 weeks |
| Pröls 1974 | Duration of intervention < 4 weeks |
| Purdy 1988 | Not a primary study (narrative overview) |
| Reid 1994 | Participants were non‐diabetic |
| Reid 1998 | Participants were non‐diabetic |
| Reid 2010 | Participants were non‐diabetic |
| Reyna 2003 | Concomitant interventions were not similar: one group received a diet based on the American Diabetic Association's nutrition recommendations, and the other group received a modified, low‐calorie diet containing a fat replacer (beta‐glucans derived from oats) and the sweeteners, sucralose and fructose |
| Ritu 2016 | Not a randomised controlled trial |
| Rodin 1990 | Participants were non‐diabetic |
| Rogers 1994 | Duration of intervention < 4 weeks |
| Sadeghi 2019 | Wrong intervention (not an NNS) |
| Samanta 1985 | Effects of an intervention with either 20 g glucose, 20 g sucrose, or 26 g honey |
| Saundby 1887 | Not a primary study (narrative overview) |
| Schatz 1977 | Not a randomised controlled trial |
| Sharafetdinov 2002 | Not a randomised controlled trial |
| Shigeta 1985 | Not a randomised controlled trial |
| Simeonov 2002 | Effect of consuming 200 mL Aronia melanocarpa juice (with artificial sweeteners, but also containing flavonoids, vitamins, minerals, trace elements) compared to no intervention |
| Skyler 1980 | Not a primary study (narrative overview) |
| Sloane 1858 | Not a primary study (narrative overview) |
| Stevens 2013 | Not a primary study (narrative overview) |
| Stoye 2008 | Not a primary study (narrative overview) |
| Sørensen 2014 | Participants were non‐diabetic |
| Taljaard 2013 | Participants were non‐diabetic |
| Tsapok 2012 | Participants were non‐diabetic |
| Tuttas 2012 | Not a primary study (narrative overview) |
| Vazquez Duran 2013 | Participants were non‐diabetic |
| Verspohl 2014 | Not a primary study (narrative overview) |
| Vorster 1987 | Duration of intervention < 4 weeks |
| Watal 2014 | Not a primary study (narrative overview) |
| Williams 1857 | Not a randomised controlled trial |
| Williams 1858 | Not a primary study (narrative overview) |
| Williams 2014 | Not a primary study (narrative overview) |
| Wills 1981 | Not a randomised controlled trial |
| Ylikahri 1980 | Not a primary study (narrative overview) |
| Zöllner 1971 | Participants were non‐diabetic |
ADA: American Dietetic Association; NNS: non‐nutritive sweetener.