Table 2.
Best FDA approved drugs obtained from Virtual screening.
| Ligands | Binding energy (kcal/mol) |
|---|---|
| Alkaloids based drugs | |
| Ergotamine | −10 |
| Dihydroergotamine | −9.5 |
| Antiviral | |
| Saquinavir | −8.7 |
| Indinavir | −8.7 |
| Cardiac glycoside | |
| Digitoxin | −9.4 |
| Deslanoside | −8.9 |
| Chlorthalidone | −8.7 |
| Anticancer compounds | |
| Dactinomycin | −9.9 |
| Irinotecan | −9.4 |
| Nilotinib | −9.4 |
| Plicamycin | −9.4 |
| Methotrexate | −8.8 |
| Eribulin | −8.7 |
| Lanreotide | −8.7 |
| Steroid based drugs | |
| Fluocinolone acetonide | −8.9 |
| Desoximetasone | −8.8 |
| Triamcinolone acetonide | −8.7 |
| Betamethasone | −8.7 |
| Other drugs | |
| Tadalafil | −9 |
| Zafirlukast | −8.9 |
| Paliperidone | −8.8 |
| Ertapenem | −8.7 |