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(A) Selectivity response of this method against mutation probes (M1~M4 refer to 1, 2, 3 and 4 base mutation) and the random sequence miR-21. The concentration of the SARS-CoV-2 RNA is 10 nM, the concentrations of mutation probes and random sequence miR-21 are 100 nM. The data error bars indicate mean ± SD (n = 3). (B) Detection results in TM buffer, 10% serum and 10% saliva sample by our method, respectively. The data error bars indicate mean ± SD (n = 3).
