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. 2020 Jul 29;167:112479. doi: 10.1016/j.bios.2020.112479

Scheme 1.

Scheme 1

A DNA nanoscaffold hybrid chain reaction (DNHCR)-based method for the detection of SARS-CoV-2 RNA. a, The synthesis of DNA nanoscaffolds based on the hybridization of H1 probes with long DNA strands produced by RCA. b, The procedure of DNHCR triggered by the SARS-CoV-2 RNA. c, The detection of the target SARS-CoV-2 RNA in the mixed solution of DNA nanoscaffolds and H2 probes.