Table 6.
Cohorts in which scattered cell death was detected after experimental SAH
Species | SAH method | Time of assessment (days) | Histological method to show cell death | Region | Refs. |
---|---|---|---|---|---|
Mouse | PCI | 2 | FJ, TUNEL, caspase 3 | C | [43] |
Mouse | PCI | 2 | FJ | C, H | [41] |
Mouse | PCI | 2 | TUNEL | C, SC, H | [40] |
Mouse | PCI | 2 | TUNEL | C, SC, H | [39] |
Mouse | CMI | 7 | NeuN | C | [37] |
Mouse | CMI | 7 | Nissl | C, H | [38] |
Mouse | EVP | 1, 14 | FJ (day 1), NeuN (day 14) | C, H | [17] |
Rat | PCI | 1, 3 | Caspase 3 & TUNEL (day 1), Nissl (day 3) | C | [70] |
Rat | CMI | 3, 5 | H&E | C, H | [16] |
Rat | EVP | 7 | Cresyl violet | H | [80] |
Rat | EVP | 2–7 | Cresyl violet, FJ, TUNEL | H | [77] |
Rat | EVP | 5 | Cresyl violet | H | [72] |
Rat | EVP | 1 | FJ, TUNEL | C | [83] |
Rabbit | CMI | 1 | TUNEL and Nissl | C | [70] |
Primate | PVC | 7 | Cresyl violet | C | [143] |
Studies are sorted by species and SAH method
C cortex, CMI cisterna magna blood injection ×1–3, EVP endovascular perforation of internal carotid artery terminus, FJ fluoro-Jade staining, H hippocampus, H&E hematoxylin–eosin staining, PCI prechiasmatic blood injection, PVC perivascular clot placement, SAH subarachnoid hemorrhage, SC subcortex, TUNEL terminal deoxynucleotidyl transferase dUTP nick end labeling