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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Neurocrit Care. 2020 Feb;32(1):238–251. doi: 10.1007/s12028-018-0650-5

Table 7.

Characteristics of cohorts that showed frank infarction after experimental SAH

Species SAH method Time of assessment Method of assessment Findings Region Refs.

Mouse EVP 2 h, 3 days MRI New or larger infarct on day 3 in 33% (5/15) of animals C [18]
Mouse EVP 3 h, 3 days MRI New or larger infarct on day 3 in 30% (3/10) of animals C [19]
Mouse EVP 1, 3 days MRI New or larger infarct on day 3 in 50% (4/8) of animals C [20]
Mouse EVP 1, 3 days MRI New or larger infarct on day 3 in 50% (5/10) of animals C [21]
Rat EVP 1 h, 2, 9 days MRI Average infarct volume doubled on day 2 C [22]
Rat EVP 1, 3 days MRI Average infarct volume increased by 29 mm3 on day 3 C, SC, H [23]
Dog CMI ? H&E Infarct in 29% (4/14) of animals CBL [120]
Primate PVC 7 days MRI Infarct in 100% (2/2) of animals C, SC [122]
Primate PVC 8 days Autopsy Infarct in 13% (1/8) of animals C [140]
Primate PVC 5 days CT Infarct in 13% (1/8) of animals C [131]
Primate PVC 5 days MRI Infarct in 8% (1/12) of animals C [130]
Primate PVC 5, 7 days MRI, CT, autopsy Infarct in 25% (2/8) of animals on day 5 or 7 C, CBL [129]
Primate PVC 7 days CT Infarct in 7% (1/15) of animals C [127]

Studies are sorted based on type of injury, followed by species and subarachnoid hemorrhage method

C cortex, CBL cerebellum, CMI cisterna magna blood injection ×1–3, CT computed tomography, EVP endovascular perforation of internal carotid artery terminus, FJ fluoro-Jade staining, H hippocampus, MRI magnetic resonance imaging, PCI prechiasmatic blood injection, PVC perivascular clot placement, SAH subarachnoid hemorrhage, SC subcortex