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. Author manuscript; available in PMC: 2020 Jul 29.
Published in final edited form as: Horm Behav. 2020 Feb 29;121:104719. doi: 10.1016/j.yhbeh.2020.104719

Table 7.

Significantly enriched interactions of DEGs indicating the gene ontology and biological pathways (KEGG & Reactome) in Female WT v. ArKO mice.

Description FDR
GO: molecular 6-Pyruvoyltetrahydropterin synthase 0.006792819
function activity
aromatase activity 0.015984047
Biological pathways Tetrahydrobiopterin (BH4) synthesis, 0.010725654
(Reactome) recycling, salvage and regulation
Metabolism of cofactors 0.010725654
Estrogen biosynthesis 0.010725654
HSF1-dependent transactivation 0.011254654
Endogenous sterols 0.011254654
Metabolism of steroid hormones 0.014391637
Biological pathways Folate biosynthesis 0.013072049
(KEGG) Steroid hormone biosynthesis 0.013072049
Ovarian steroidogenesis 0.013072049
Metabolic pathways 0.013072049
Longevity regulating pathway-multiple species 0.013072049