Comparison 1. 50% pain relief using pain relief measures.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Paracetamol versus placebo: number of people with at least 50% pain relief at 4 hours	16	1498	Risk Ratio (M‐H, Random, 95% CI)	2.85 [1.89, 4.29]
1.1 Up to 1000 mg of paracetamol	10	710	Risk Ratio (M‐H, Random, 95% CI)	1.96 [1.34, 2.86]
1.2 1000 mg or more	6	788	Risk Ratio (M‐H, Random, 95% CI)	4.56 [2.86, 7.27]
2 Paracetamol versus placebo: number of people with at least 50% pain relief at 6 hours	13	1155	Risk Ratio (M‐H, Random, 95% CI)	3.32 [1.88, 5.87]
2.1 Up to 1000 mg of paracetamol	6	378	Risk Ratio (M‐H, Random, 95% CI)	1.89 [0.98, 3.67]
2.2 1000 mg or more	7	777	Risk Ratio (M‐H, Random, 95% CI)	4.21 [2.97, 5.98]