Comparison 2. 50% pain relief using pain intensity measures.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Paracetamol versus placebo: number of people with at least 50% pain relief at 4 hours	17	1658	Risk Ratio (M‐H, Random, 95% CI)	4.87 [2.83, 8.37]
1.1 Up to 1000 mg of paracetamol	10	737	Risk Ratio (M‐H, Random, 95% CI)	4.33 [2.19, 8.58]
1.2 1000 mg or more	8	921	Risk Ratio (M‐H, Random, 95% CI)	6.46 [2.34, 17.85]
2 Paracetamol versus placebo: number of people with at least 50% pain relief at 6 hours	13	1184	Risk Ratio (M‐H, Random, 95% CI)	3.41 [2.34, 4.97]
2.1 Up to 1000 mg of paracetamol	6	403	Risk Ratio (M‐H, Random, 95% CI)	2.67 [1.46, 4.90]
2.2 1000 mg or more	8	781	Risk Ratio (M‐H, Random, 95% CI)	3.96 [2.52, 6.23]