| Methods |
Randomised, parallel group, double blind study |
| Participants |
298 participants randomised to 6 groups, withdrawals unclear (51 from all groups)
Number randomised to intervention: male 13, female 24, mean age 22.5
Number randomised to placebo: male 11, female 27, mean age 23.5
Number of third molars removed: mean for intervention and placebo 1.9
Baseline pain intensity: mean for intervention 2.41 (moderate 22, severe 15), mean for placebo 2.42 (moderate 22, severe 16)
Setting ‐ outpatients (USA) |
| Interventions |
Paracetamol 500 mg versus placebo
Formulation not stated
Anaesthesia: not stated |
| Outcomes |
PI at 4 hours: categorical scale 0‐3 (none ‐ severe)
PR at 4 hours: categorical scale 0‐4 (none ‐ complete)
Global assessment: categorical scale 0‐4 (poor ‐ excellent)
Adverse events table |
| Notes |
Sponsored unclear |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
