| Methods |
Randomised, parallel group, double blind study |
| Participants |
248 participants randomised to 5 groups, withdrawals unclear (48 from all groups)
Number randomised to intervention: male 15, female 22, mean age 22.2
Number randomised to placebo: male 13, female 24, mean age 23.7
Number of third molars removed: not stated
Baseline pain intensity: mean for intervention 2.2 (moderate 29, severe 9), mean for placebo 2.3 (moderate 26, severe 11)
Setting not stated (USA) |
| Interventions |
Paracetamol 650 mg versus placebo
Formulation: not stated
Anaesthesia: LA or GA |
| Outcomes |
PI at 4 hours: categorical scale 0‐3 (none ‐ severe)
PR at 4 hours: categorical scale 0‐4 (none ‐ complete)
Global assessment: categorical scale 0‐4 (poor ‐ excellent)
Total number of adverse events and number of people with adverse events reported |
| Notes |
Sponsored by
Adria Laboratories |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
