| Methods |
Randomised, parallel group, double blind study |
| Participants |
177 participants randomised to 4 groups, no withdrawals
Number randomised to intervention: male 23, female 27, mean age 23.6
Number randomised to placebo: male 12, female 14, mean age 22.7
Number of third molars removed: not stated
Baseline pain intensity: mean for intervention: categorical 2.3, VAS 60.3, mean for placebo: categorical 2.2, VAS 62.8
Setting ‐ Georgetown University Hospital (USA) |
| Interventions |
Paracetamol 1000 mg versus placebo
Formulation: not stated
Anaesthesia: LA or LA and SED |
| Outcomes |
PI at 4 hours and 6 hours: categorical scale 0‐3 (none ‐ severe), VAS scale 0‐100 mm (none ‐ worst pain imaginable)
PR at 4 hours and 6 hours: categorical scale 0‐4 (no relief ‐ complete relief)
Global assessment: not stated
Adverse effects table |
| Notes |
Sponsored by
Whitehall‐Robins |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
