| Methods |
Randomised, parallel group, double blind study |
| Participants |
338 participants enrolled in 4 groups, withdrawals unclear (40 from all groups)
Number randomised to intervention: male 28, female 44, mean age 27.9, age range 18‐49
Number randomised to placebo: male 28, female 48, mean age 27.2, age range 18‐45
Number of third molars removed: not stated
Baseline pain intensity: range for intervention and placebo given together as average 21.4 (2.08 ‐ 2.19)
Setting not stated (Italy) |
| Interventions |
Paracetamol 500 mg versus placebo
Formulation: tablets
Anaesthesia: not stated |
| Outcomes |
PI at 4 hours: categorical scale 0‐3 (none ‐ severe)
PR at 4 hours: categorical scale 0‐4 (none ‐ complete)
Global assessment: categorical 0‐4 (negative ‐ very good)
Adverse effects table |
| Notes |
Sponsored ‐ unclear |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
