Olson 2001.

Methods	Randomised, parallel group, double blind study
Participants	239 participants randomised to 4 groups, no withdrawals Number randomised to intervention: male 22, female 44, mean age 22.2 Number randomised to placebo: male 11, female 28, mean age 23.9 Number of third molars removed/patient: intervention ‐ (1/1), (2/64), (3/1), (4/0), placebo ‐ (1/1), (2/38), (3/0), (4/0) Baseline pain intensity: mean for intervention 2.86 (moderate 9, severe 57) mean for placebo 2.9 (moderate 4, severe 35) Setting: University of Puerto Rico School of Dentistry (Puerto Rico)
Interventions	Paracetamol 1000 mg versus placebo Formulation: caplets Anaesthesia: LA
Outcomes	PI at 4 hours and 6 hours: categorical scale 0‐3 (none ‐ severe) PR at 4 hours and 6 hours: categorical scale 0‐4 (none ‐ complete relief) Global assessment: categorical scale 0‐4 (poor ‐ excellent) Adverse effects table
Notes	Sponsored by Whitehall Robins
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate