| Methods |
Randomised, parallel group, double blind study |
| Participants |
147 participants randomised to 4 groups, withdrawals unclear (8 from all groups)
Number randomised to intervention: male 16, female 16, mean age 24.7
Number randomised to placebo: male 16, female 17, mean age 24.4
Number of third molars removed: not stated
Baseline pain intensity: mean for intervention approx 55, mean for placebo, approx 45
Setting not stated (Norway) |
| Interventions |
Paracetamol 1000 mg versus placebo
Formulation: tablets
Anaesthesia: LA |
| Outcomes |
PI at 4 hours and 6 hours: VAS scale 0‐100 mm (none ‐ pain cannot be worse)
PR at 4 hours and 6 hours: VAS scale 0‐100 mm (complete relief ‐ no relief) reversed for statistical analysis
Global assessment: not stated
Adverse effects table |
| Notes |
Sponsored by
Apothekernes Laboratorium |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
