| Methods |
Randomised, parallel group, double blind study |
| Participants |
182 participants randomised to 6 groups, no withdrawals (only patients with moderate to severe pain were randomised)
Number randomised to intervention: male 6, female 24, mean age 21.9
Number randomised to placebo: male 14, female 16, mean age 23
Number of third molars removed: not stated
Baseline pain intensity: mean for intervention 2.00, mean for placebo 2.00
Setting: University of Puerto Rico School of Dentistry Clinic |
| Interventions |
Paracetamol 650 mg versus placebo
Formulation: capsules
Anaesthesia: LA |
| Outcomes |
PI at 4 hours and 6 hours: categorical scale 0‐3 (none ‐ severe)
PR at 4 hours and 6 hours: categorical scale 0‐4 (none 0% ‐ complete 100%)
Global assessment: categorical 0‐3 (poor ‐ excellent)
Overall improvement 1‐7 (very much worse ‐ very much better)
Adverse effects reported by number of patients with adverse events |
| Notes |
Sponsored by
Upjohn |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
