Table 4.

Ongoing studies of AF screening

Study	Country	Status	N	Modality	Approach	Endpoint
DANCAVAS74	Denmark	Nearly complete	35,000	3-lead ECG	One-time	All-cause mortality
STROKESTOP II66	Sweden	Nearly complete	8,000	Zenicor single-lead ECG	Twice daily for 14 days	New-onset AF Initiation of OAC
SCREEN-AF75	Canada	Recently completed	856	Zio patch monitor, WatchBP oscillometric device	2 weeks at start and at 3 months	New-onset AF
AF-CATCH76	China	Follow-up	7,641	AliveCor single-lead ECG	1x/yr vs. 4x/yr vs. 1x/wk in 1st month	New-onset AF
MonDAFIS77	Germany	Follow-up	3,470	Mobile telemetry	Post-stroke, up to 7 days	Oral anticoagulation
D2AF78	Netherlands	Ongoing	19,200	MyDiagnostick single-lead ECG, WatchBP oscillometric device	One-time	New-onset AF
LOOP79	Denmark	Ongoing	6,000	Implantable loop recorder	4 years continuous	Stroke or systemic embolism
mSToPS48	United States	Ongoing	6,000	Zio patch monitor	2–4 weeks	Stroke, systemic embolism, myocardial infarction, death
VITAL-AF80	United States	Ongoing	35,000	AliveCor single-lead ECG	At each encounter	New-onset AF
GUARD-AF56	United States	Ongoing	52,000	Zio patch monitor	2 weeks	Stroke Major bleeding
London Pharmacy Study81	United Kingdom	Starting soon	600	Pulse palpation, AliveCor single-lead ECG	One-time	Test accuracy of screening modalities
SAFER82	United Kingdom	Ongoing	120,000	Zenicor single-lead ECG	Twice daily for 14 days	Stroke
Fitbit Heart Study61	United States	Ongoing	100,000	Wrist-based PPG	Wearable PPG-based algorithm followed by ECG patch	New-onset AF