Table 5.

Antihyperglycemic Activity of a Single Dose of Leaf Crude Extract and Solvent Fractions on Diabetic Mice.*

Group	Blood glucose level (mg/dL)
	0 hour	2 hours	4 hours	6 hours	8 hours
DW10	342.83 ± 6.98	356.67 ± 7.96	334.67 ± 11.65	330.33 ± 9.89	324.83 ± 7.67n3
GLC5	338.33 ± 12.06	283.33 ± 11.14β2,n3	216.33 ± 9.67β3,n3	172.17 ± 8.99 β3,n3	160.33 ± 5.17β3,n3
BAC100	328.67 ± 20.05	309.00 ± 17.87	284.67 ± 18.67	244.83 ± 19.55n3	219.00 ± 10.67β2,n3
BAC200	329.67 ± 17.31	316.17 ± 17.35	293.83 ± 15.08	233.83 ± 17.54β3,n3	208.50 ± 6.44β3,n3
BAC400	352.67 ± 11.62	325.67 ± 10.78	260.33 ± 17.67β3,n3	214.67 ± 12.36β3,n3	182.00 ± 11.35β3,n3
CFF100	347.50 ± 8.81	352.00 ± 8.45	341.67 ± 10.58	333.67 ± 11.26	321.00 ± 13.05
CFF200	334.00 ± 6.77	326.83 ± 9.09	314.67 ± 14.67	294.33 ± 11.04β1	268.33 ± 8.58β3
CFF400	355.83 ± 6.52	335.83 ± 6.77	320.17 ± 16.32β1	290.00 ± 8.27β3	264.33 ± 9.79β3,n1
EAF100	350.67 ± 7.92	340.00 ± 7.79	322.00 ± 12.37	305.00 ± 9.52β1	273.17 ± 13.40β3
EAF200	365.50 ± 5.58	347.17 ± 4.71	321.00 ± 20.24β3	285.83 ± 15.64β3	275.50 ± 7.08β3
EAF400	344.67 ± 9.88	318.00 ± 9.27	291.17 ± 19.35β3	241.50 ± 13.68β3,n3	230.00 ± 14.43β3,n3
AQF100	347.50 ± 9.02	332.83 ± 6.78	310.00 ± 11.87	292.50 ± 12.23β2	252.50 ± 11.74β3,n2
AQF200	339.50 ± 6.67	315.83 ± 10.23	286.17 ± 15.27β2	265.50 ± 10.07β3,n2	247.50 ± 9.48β3,n2
AQF400	362.33 ± 7.13	332.67 ± 6.85β1	293.83 ± 14.42β3	239.33 ± 17.52β3,n3	214.83 ± 7.98β3,n3

Abbreviations: BAC, Bersama abyssinica leaf crude extract; DW, distilled water; CFF, chloroform fraction; EAF, ethyl acetate fraction; AQF, aqueous fraction; GLC, glibenclamide.

* Each value represents mean ± SEM; n = 6 for each treatment. ⁿCompared with the negative control, ^βcompared with baseline blood glucose level. ¹ P < .05, ² P < .01, ³ P < .001,