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. 2020 Jul 28;48(7):0300060520943792. doi: 10.1177/0300060520943792

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — The pro-apoptotic effects of curcumin were attenuated using an miR-28-5p inhibitor in OCI-LY7 cells. OCI-LY7 cells were transfected with an miR-28-5p inhibitor or negative control (NC). The cells were incubated with or without curcumin (40 μM) for 48 hours. (a) TdT-mediated dUTP nick-end labeling (TUNEL) staining. (b) The percentage of TUNEL-positive cells. (c) The immunoblot bands of caspase-3 and cleaved caspase-3. (d) The relative protein levels of cleaved caspase-3. (e) The relative protein levels of caspase-3. N = 6. Compared with the control group, *P < 0.05, **P < 0.01, ***P < 0.001. Compared with the curcumin group, #P < 0.05, ##P < 0.01. Scale bar equal to 25 μm.