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. 2020 Jun 18;60(7):3508–3517. doi: 10.1021/acs.jcim.0c00280

Figure 1.

Figure 1

Series of macrocyclic model systems.61 The model compounds share a common ring scaffold but vary in their side chains. These modifications were specifically designed to achieve different conformational preferences and cell permeabilities. Reprinted with permission from ref (61). Copyright 2018 American Chemical Society.