Ghazizadeh 2014.

Study characteristics
Methods	Parallel randomised controlled trial
Participants	Department of Obstetrics and Gynecology and Maternal‐Fetal and Neonatal Research Center and Breastfeeding Research Center, Tehran University of Medical Sciences Inclusion criteria Menorrhagia; hysterectomy candidate Age 35 to 45 Hormonal treatment for at least 6 months without adequate improvement Exclusion criteria Pregnancy; null gravid; abnormal Pap smear; genital infection Hormonal disorder Hormonal treatment Anomalous uterus Any disorder inside the uterine cavity or abnormal endometrial biopsy Coagulative disorder Submocusal myomas > 2 cm and intramural myomas that moved the endometrial layer Uterine cavity > 11 cm Setting: Tehran, Iran Time frame: October 2009 to November 2010
Interventions	Bipolar endometrial ablation (Novasure) (n = 30) Hysteroscopic endometrial resection (HER) (n = 32) Mirena (lg‐IUS) (n = 48)
Outcomes	Decreased menstrual blood loss Interaction between bleeding and normal activity Anaemia (estimated 6.8 mg/dL as cut‐off for anaemia) Patients’ satisfaction (checklist 6 months' follow‐up; some up to 12)
Notes	Funding: not specified; includes the statement "No competing financial interest" Outcomes do not match correctly on the report. Study authors contacted for more details, no response
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	The title says RCT, but no data provided on the randomisation process
Allocation concealment (selection bias)	Unclear risk	No information
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open label, lack of blinding likely to influence outcome.
Blinding of participants and personnel (performance bias) Haematin alkaline, Haemoglobin All outcomes	Low risk	Not blinded, lack of blinding unlikely to influence the outcome.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not specified, lack of blinding likely to influence outcome.
Blinding of outcome assessment (detection bias) (Haematine alkaline and haemoglobin) All outcomes	Unclear risk	Not blinded, lack of blinding unlikely to influence the outcome.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Numbers in tables do not match numbers in text; study authors have been contacted for confirmation
Selective reporting (reporting bias)	High risk	No quantification of bleeding; not specified at what time satisfaction was measured
Other bias	High risk	Past medical history was positive in 12% Mirena, 13.3% Novasure, and 53.1% of HER (P < 0.0001) Ultrasonography was performed in 35.4% of patients in the Mirena group, 66.7% in the Nova‐Sure group, and 96.8% in the hysteroscopic endometrial resection group (P < 0.0001)