Table II.
Functional enrichment analysis of hub genes.
A, Biological process (GO) | |||
---|---|---|---|
Term/pathway | Description | False discovery rate | |
GO:1903047 | Mitotic cell cycle process | 2.92×10−13 | |
GO:0051301 | Cell division | 8.13×10−12 | |
GO:0000280 | Nuclear division | 1.59×10−7 | |
GO:0140014 | Mitotic nuclear division | 3.70×10−7 | |
GO:0051726 | Regulation of cell cycle | 3.82×10−7 | |
B, Molecular function (GO) | |||
Term/pathway | Description | False discovery rate | |
GO:0008022 | Protein C-terminus binding | 0.0122 | |
GO:0005524 | ATP binding | 0.0122 | |
GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | 0.0122 | |
GO:0042826 | Histone deacetylase binding | 0.0153 | |
GO:0003682 | Chromatin binding | 0.0153 | |
C, Cellular component (GO) | |||
Term/pathway | Description | False discovery rate | |
GO:0015630 | Microtubule cytoskeleton | 2.43×10−5 | |
GO:0005819 | Spindle | 2.43×10−5 | |
GO:0044430 | Cytoskeletal part | 7.34×10−5 | |
GO:0005815 | Microtubule organizing center | 0.00033 | |
GO:0005829 | Cytosol | 0.00065 | |
D, KEGG pathways | |||
Term/pathway | Description | False discovery rate | |
hsa04115 | p53 signaling pathway | 9.70×10−5 | |
hsa04114 | Oocyte meiosis | 0.00023 | |
hsa04110 | Cell cycle | 0.00023 | |
hsa04914 | Progesterone-mediated oocyte maturation | 0.0047 | |
hsa04120 | Ubiquitin mediated proteolysis | 0.0075 |
GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.