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CENPM function may be regulated via the mTOR/p70S6K signaling pathway. (A) The phosphorylation levels of p70S6K and mTOR were significantly reduced when CENPM was knocked down by si-RNA1 and si-RNA2. (B and C) Densitometric analysis of the protein bands in A. The data were obtained from at least three independent experiments. *P<0.05, **P<0.001, ****P<0.0001 compared to si-NC. CENPM, centromere protein M; si-RNA, small interfering RNA; mTOR, mammalian target of rapamycin.
